poulin_small-150x150We are delighted to announce that Dr. Myles Poulin will join the Department this summer as an Assistant Professor.

Research Interests. Dr. Poulin’s research interests are in Bioorganic Chemistry and Chemical Biology, with a specific focus on glycobiology and membrane protein biophysics. The main goal of Dr. Poulin’s research program is to develop new tools to study the function of exopolysaccharides in the development of bacterial biofilms and to understand the role of those exopolysaccharides in bacterial infections. Understanding the mechanism of biofilm formation at the molecular level may well help design and discover inhibitors that can be used to treat bacterial infections.

One of the goals of the Poulin lab will be to develop new tools and new methods to examine the molecular basis of bacterial exopolysaccharide biosynthesis and membrane transport. These efforts will help clarify the role that these polysaccharides play in the structure and function of bacterial biofilms. The Poulin lab will use chemical, enzymatic and NMR based methods to study the enzymes involved in exopolysaccharide biosynthesis and excretion in bacteria that form biofilms. Researchers in the Poulin group will employ a multidisciplinary approach to study substrate recognition and membrane transport by enzymes involved in biofilm formation.

Biography. Myles Poulin grew up in British Columbia, Canada and he earned a B.S. in Biochemistry & Molecular Biology in 2007 from the University of Northern British Columbia. He then moved to the University of Alberta to carry out his research in mechanistic enzymology of glycosyltransferases under the guidance of Prof. Todd Lowary. After earning his PhD in 2012, Myles moved to New York City as an NSERC postdoctoral fellow with Prof. Vern Schramm at the Albert Einstein College of Medicine. There he has used experimental and computational tools to analyze the transition state of lysine methyltransferase enzymes.



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