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PrintOsnat Herzberg
Professor
Personal Data
Office Phone: 240-314-6245
Office Address: IBBR, University of Maryland at Shady Grove
Email: osnat@umd.edu
Education
Ph.D. Biochemistry, Weizmann Institute, 1982
Research Interests
Structural Biology, Protein Crystallography.
We are Structural Biologists interested in the relationship between the function and structure of proteins. We use X-ray crystallography to determine the structures of our molecules of interest, and various computational tools to analyze these structures. Functional studies are carried out in our laboratory and/or in collaboration with other investigators. Some of our projects include:
-Structural Genomics
(a) Structural Genomics of bacterial proteins of unknown function.
(b) The structural consequences of alternative splicing.
-Giardia Drug Targets - structure, function and inhibitor design.
-Function, structure and evolution of the PEP mutase/isocitrate lyase superfamily.
-The pyruvate phosphate dikinase and Enzyme I molecular machines: Spare parts and swiveling domain mechanism.
