College of Computer, Mathematical and Natural Sciences

Research Groups

Primary Investigator
Research Overview
Millard Alexander
Theoretical study of inelastic and reactive molecular collisions, particularly those involving free radicals; the photofragmentation of small molecules; and the structure and energetics of weakly bound complexes involving open-shell species
Understanding the Chemical Universe:
Study Combining Experiment and Theory Affirms Key Premise of Quantum Chemistry
Jeffery Davis
Supramolecular Chemistry, Molecular Recognition, Nanoscience and Nanotechnology, Bioorganic Chemistry, Separations Chemistry, NMR Spectroscopy, Synthetic Ion Channels
Kwaku Dayie
Structure, interactions, dynamics, and function of RNA complexes involved in catalysis and gene regulation; chemical biological methods of labeling RNAs; RNA-Drug interactions, NMR methods development for large macromolecules
Michael P. Doyle

Asymmetric catalysis with metal carbenes and Lewis acids; structural design and chemistry of dirhodium carboxamidates; catalytic chemical oxidations; bioinorganic chemistry of nitrogen oxides and nitrosyls; reductions by organosilanes.

 

 

Bryan Eichhorn

Materials Chemistry, Materials Synthesis, Heterogeneous Catalysis, Fuel Cell Research, Transition Metal Main Group Clusters (Zintl Ions), NMR Spectroscopy, Crystallography.

Catherine Fenselau
Modification of protein structures and abundances by disease and chemotherapy; New methods for mass spectrometry-based proteomics; Rapid identification and forensic analyses of pathogens using mass spectrometry, proteomics and bioinformatics.
John T. Fourkas
Ultrafast nonlinear optical spectroscopy of liquids; dynamics of nanoconfined liquids; nonlinear optical microscopy; nontraditional approaches to micro- and nanofabrication; dynamics of single molecules and single nanoparticles.
David Fushman
Structure, dynamics, stability, and function of biological macromolecules. Structural biology and molecular mechanisms of intracellular signaling. Ubiquitin-proteasome system. Structure and dynamics of multidomain proteins. Development and application of new robust theoretical and experimental approaches to protein structure and dynamics in order to understand their roles in protein stability and function.
Lyle Isaacs

The Isaacs group is interested in supramolecular and synthetic chemistry with an emphasis on molecular container molecules known as cucurbit[n]urils (CB[n]). Molecular containers - most commonly cyclodextrins - have enormous everyday applications including scent release and odor control (e.g. Febreeze) in consumer products and foodstuffs. We believe that CB[n] containers will supplant the cyclodextrins in a variety of practical and academic applications with all the attendant societal impact.

Jason Kahn
  • DNA structure and topology in multi–protein DNA complexes.
  • Role of DNA structure in transcription.
  • Construction of nanoscale objects using DNA and protein-DNA complexes.
  • Application of biophysical methods and computer simulation to complex systems.
  • Detailed research description (pdf)